Endocrine Abstracts

Introduction: Celiac disease is an autoimmune disorder related to gluten ingestion in genetically predisposed individuals. Its clinical expression is polymorphic, rendering it a true systemic disease, and its management is based on a gluten-free diet (GFD). Autoimmune endocrinopathies are disorders affecting endocrine glands such as the thyroid or adrenal glands, also stemming from autoimmune reactions with complex pathophysiological mechanisms involving environmental, genetic...

Introduction: Primary hyperparathyroidism is a common pathology. The association of papillary thyroid carcinoma and primary hyperparathyroidism has been reported in 2.3–4.3% of patients operated on for primary hyperparathyroidism.We report the case of a patient with papillary thyroid carcinoma revealed by primary hyperparathyroidismObservation: 53-year-old patient admitted for management of primary hyperparathyroidism. A cervical ultrasound revealed...

Introduction: Familial hypercholesterolemia is an autosomal dominant genetic disease linked to a mutation in 3 genes involved in the catabolism of LDL particles. It is characterized by an exclusive increase in low-density lipoproteins (LDL). It is associated with a high risk of premature cardiovascular complications. We report the case of a patient with familial hypercholesterolemia.Case: 44-year-old patient, From a first-degree consanguineous marriage, ...

IntroductionEctopic thyroid tissue is a rare clinical entity, with a prevalence of 1: 300 000 in the general population. The ectopic tissue may be located anywhere from the base of the tongue to the diaphragm, the most frequent sites being lingual, thyroglossal, laryngotracheal, and lateral cervical regions. It may also occur in less frequent sites such as the esophagus, mediastinum, heart, adrenal glands, and pancreas. The mediastinum is the most freque...

IntroductionType 1 diabetes mellitus (T1DM) is an autoimmune disease in which pancreatic βcells are destroyed, generating an incapacity to maintain appropriate insulin and glucose concentration. On the other hand, type 2 diabetes mellitus (T2DM) is associated with varying degrees of insulin resistance (IR) and relative insulin deficiency. The association of T1DM and the clinical features of T2DM as obesity, hypertension, dyslipidemia, or metabolic s...

IntroductionCarney complex (CNC) is an extremely rare genetic syndrome of pigmented skin lesions, endocrine hyper-function and myxoma. Given its diverse clinical manifestations, CNC is often misdiagnosed. Recognition of some special clinical manifestations and imaging features may help with the diagnosis. We report the case of CNC with endocrine and cutaneous tumors.CaseA 50 years old female patient followed ...

Introduction: Primary hyperparathyroidism (PHPT) represents a prevalent medical condition frequently characterized by asymptomatic manifestations. The etiology of PHPT is predominantly attributed to parathyroid adenomas, accounting for 85% of cases, with 10% demonstrating ectopic localization. The prevalence of asymptomatic presentation poses distinctive challenges in both diagnostic and therapeutic realms, necessitating a nuanced approach to effectively address the complexiti...

Introduction: Primary hyperparathyroidism (PHPT) is a common endocrine disease secondary to autonomous hypersecretion of parathyroid hormone (PTH) by one or more parathyroid glands. It is a predominantly female disease and most often asymptomatic. Its positive diagnosis is purely biological. Its curative treatment is surgical.Patients & methods: This retrospective descriptive study encompasses 83 patients who were hospitalized and longitudinally moni...

Introduction: Primary hyperparathyroidism (PHPT) is a common endocrinopathy caused by inappropriate PTH secretion by the parathyroid glands, which leads to alterations in phosphocalcic metabolism. The aim of our study is to determine the prevalence of complications of PHPT.Materials and Methods: Retrospective descriptive study of 83 patients with primary hyperparathyroidism collected over a period of 07 years (between 2015 and 2022) in the endocrinology ...

Introduction: Multiple endocrine neoplasia type 2A (MEN2A) is a rare genetic condition characterized by medullary thyroid cancer (MTC), often accompanied by primary hyperparathyroidism (PHPT) in 20% to 30% of cases which is usually detected while investigating other issues and is not commonly the initial indicator of the condition. This study aims to describe the specific features of primary hyperparathyroidism (PHPT) in MEN2A, providing insights into its distinct characterist...